ArticleFrontiers in insect science2026
Comparative transcriptomic analysis of functional and metabolic changes in mass-reared and wild
Article in Frontiers in insect science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Mass rearing for the Sterile Insect Technique (SIT) may induce transcriptomic changes that influence post-release performance. We compared head transcriptomes of two mass-reared Methods: RNA-seq data were analyzed to assess transcriptomic differentiation, differential gene expression, Gene Ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, and chemosensory gene expression profiles among the three groups. Results: Principal component analysis clearly separated the mass-reared strains from wild host-associated individuals. More than 1,300 differentially expressed genes were identified per strain, with gene repression predominating and enrichment of functions related to translation, cellular energy metabolism, RNA processing, and metabolic regulation. Both mass-reared strains shared signatures of metabolic adjustment but also displayed strain-specific patterns. The Bisexual strain showed signatures associated with stress response, immunity, and mitochondrial quality control, whereas Tap-7 showed enrichment of pathways related to calcium regulation, secretion, detoxification, and folate metabolism. Both strains also exhibited reorganization of chemosensory gene expression, including conservation of receptors and co-receptors such as Discussion: These results indicate that mass-reared
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