Observational studyFrontiers in endocrinology2026
Combined TyG index and systemic inflammation indices as predictors for asteroid hyalosis: a hospital-based cross-sectional study.
Observational study in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This research explored the laboratory indicators and derived indicators of patients with asteroid hyalosis (AH) in patients with diabetic retinopathy (DR), calculated the TyG index and systemic immune-inflammatory (SII) index, so as to identify the systemic pathogenic factors of AH in DR patients. Methods: The data were gained from patients who underwent vitrectomy for proliferative DR (PDR) in Hebei Eye Hospital. Depending on the presence or absence of AH, these participants were classified into the AH group (n = 45; 27 males, 18 females) and the non-AH group (n = 90; 48 males, 42 females). The laboratory indicators, TyG index, and SII index were compared between the two groups. A statistical analysis was implemented on their age, gender, laboratory indicators, TyG index, and SII index. Results: The patients in the AH group exhibited remarkably higher cholesterol (4.85 Conclusion: The abnormal lipid metabolism, inflammatory activation, and poor glycemic control in patients with AH are more pronounced than in DR patients without AH. Cerebral infarction and AH share overlapping systemic pathological mechanisms.
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