Evidence map›Paper›PMID 42676386›Full record

ArticleFrontiers in oncology2026

Prognostic significance of CD56 expression in newly diagnosed multiple myeloma and its correlation with clinicopathological features.

Pei Pei, Jiaxin Lv, Boyuan Zheng, Kangqi Lv, Junjun Bai, Lin Li, Qinglin Song, Zhizhong Lu, Han Xu, Yi Zhang

Abstract read
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Pei Pei *Laboratory of Hematological Diseases, Jiaozuo People's Hospital Affiliated to Henan Medical University, Jiaozuo, Henan, China.
Jiaxin Lv *Laboratory of Hematological Diseases, Jiaozuo People's Hospital Affiliated to Henan Medical University, Jiaozuo, Henan, China.
Boyuan Zheng *School of Clinical Medicine, Henan University, Kaifeng, China.
Kangqi LvLaboratory of Hematological Diseases, Jiaozuo People's Hospital Affiliated to Henan Medical University, Jiaozuo, Henan, China.
Junjun BaiDepartment of Hematology, Jiaozuo People's Hospital Affiliated to Henan Medical University, Jiaozuo, Henan, China.
Lin LiLaboratory of Hematological Diseases, Jiaozuo People's Hospital Affiliated to Henan Medical University, Jiaozuo, Henan, China.
Qinglin SongLaboratory of Hematological Diseases, Jiaozuo People's Hospital Affiliated to Henan Medical University, Jiaozuo, Henan, China.
Zhizhong LuDepartment of Clinical Laboratory, Jiaozuo People's Hospital Affiliated to Henan Medical University, Jiaozuo, Henan, China.
Han XuSchool of Basic Medical Sciences & School of Public Health, Faculty of Medicine, Yangzhou University, Yangzhou, Jiangsu, China.
Yi ZhangLaboratory of Hematological Diseases, Jiaozuo People's Hospital Affiliated to Henan Medical University, Jiaozuo, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the correlation of CD56 expression with clinical prognosis and adverse prognostic indicators in patients with newly diagnosed multiple myeloma (NDMM). Methods: We conducted a retrospective cohort study of 153 NDMM patients treated at Jiaozuo People's Hospital Affiliated to Henan Medical University between May 2014 and August 2024. Patients were stratified into the bortezomib cohort and the non-bortezomib cohort based on their treatment regimens, and were further divided into CD56 Results: No statistically significant differences in median progression-free survival (PFS) or overall survival (OS) were observed between the CD56 Conclusion: Bortezomib-based therapy may attenuate the adverse prognostic impact associated with CD56 deficiency. CD56 expression has prognostic significance in NDMM and is closely correlated with multiple adverse clinicopathological indicators; however, it does not serve as an independent prognostic factor for NDMM patients.

Indexed as

bortezomibCD56newly diagnosed multiple myelomaoverall survivalprogression-free survival

Identifiers

PMID42676386
PMCPMC13526565

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