ArticleFrontiers in nutrition2026
Association between red blood cell distribution width to albumin ratio and pneumonia risk in acute ischemic stroke: evidence from two independent cohorts.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Pneumonia is a common and severe complication in acute ischemic stroke (AIS) patients, particularly those requiring intensive care. Early prediction of pneumonia risk can enable timely interventions and improve clinical outcomes. The Red Blood Cell Distribution Width to Albumin Ratio (RAR), combining markers of inflammation (RDW) and nutritional status (albumin), has potential as a predictor of pneumonia risk in AIS patients. Methods: This retrospective cohort study included AIS patients from MIMIC-IV ( Results: Elevated RAR was significantly associated with an increased risk of pneumonia in both cohorts. In the MIMIC-IV cohort, the incidence of pneumonia was higher in the highest RAR group (T3) compared to the lowest (T1) (21.75% vs. 7.11%, Conclusion: RAR was independently associated with pneumonia during ICU stay among patients with AIS. As a readily available and low-cost biomarker, RAR may serve as an adjunctive marker for early risk stratification. However, its discriminatory performance was modest, and its clinical value beyond established predictors remains uncertain. Prospective studies are needed to confirm these findings.
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