Trial reportFrontiers in oncology2026
Effects of an intensive pulmonary rehabilitation program on postoperative pulmonary complications in frail elderly patients undergoing hepatobiliary and pancreatic surgery: a randomized controlled trial.
Trial report in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Background: Frail elderly patients undergoing hepatobiliary-pancreatic (HBP) surgery face a substantially elevated risk of postoperative pulmonary complications (PPCs), which are associated with increased mortality, extended morbidity, and greater healthcare costs. Although the "I Cough" pulmonary rehabilitation program is a well-established preventive strategy for PPCs, its clinical effectiveness is often limited by suboptimal patient adherence. This randomized controlled trial was therefore conducted to determine whether a nurse-led intensive pulmonary rehabilitation exercises (IPREs) program could improve compliance and reduce the occurrence of PPCs in this highly susceptible population. Methods: A total of 160 participants were randomly assigned to two groups. Eighty patients in the intervention (IPREs) group received IPREs, whereas 80 patients in the control group underwent conventional self-pulmonary rehabilitation training. The incidences of PPCs and other postoperative outcomes were compared between the two groups. Results: The median compliance rate with pulmonary rehabilitation exercises was significantly higher in the IPREs group than in the control group (100.00% [IQR 83.33-100.00%] vs. 33.33% [IQR 33.33-66.67%]; Conclusions: The nurse-led intensive pulmonary rehabilitation program significantly improved compliance with pulmonary rehabilitation exercises, reduced the incidence of PPCs, and shortened postoperative hospitalization in frail elderly patients undergoing HBP surgery. Clinical trial registration: https://www.chictr.org.cn, identifier ChiCTR2000040021.
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