ArticleCNS neuroscience & therapeutics2026
Hierarchically and Temporally Distinct Ca
Yao-Hua Liu, Tian-Yu Zhao, Jin Cheng, Li-Ming Liu, Sha-Sha Tao, Yu-Jing Chen, Jia-Qi Zhu, Fen-Sheng Huang, Zhi-Ping Cai, Fei Li and 1 more
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In one paragraphArticle in CNS neuroscience & therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Yao-Hua LiuDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Basic Medical College, The Fourth Military Medical University, Xi'an, China.ORCID https://orcid.org/0009-0007-2166-7137 Tian-Yu ZhaoDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Basic Medical College, The Fourth Military Medical University, Xi'an, China.ORCID https://orcid.org/0009-0009-7073-0977 Jin ChengDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Basic Medical College, The Fourth Military Medical University, Xi'an, China.
Li-Ming LiuDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Basic Medical College, The Fourth Military Medical University, Xi'an, China.
Sha-Sha TaoDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Basic Medical College, The Fourth Military Medical University, Xi'an, China.
Yu-Jing ChenDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Basic Medical College, The Fourth Military Medical University, Xi'an, China.
Jia-Qi ZhuDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Basic Medical College, The Fourth Military Medical University, Xi'an, China.
Fen-Sheng HuangInstitute of Neuroscience and Physiology, Göteborg University, Göteborg, Sweden.
Zhi-Ping CaiDepartment of Human Anatomy, Baotou Medical College, Baotou, China.
Yun-Qing LiDepartment of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, Basic Medical College, The Fourth Military Medical University, Xi'an, China.ORCID https://orcid.org/0000-0002-3707-3348 Funding
Brain Science and Brain-like Intelligence Technology-National Science and Technology Major Project 2021ZD0204403National Natural Science Foundation of China 82130034National Natural Science Foundation of China 82221001National Natural Science Foundation of China 82471254
6 · The paper itselfAbstract
backgroundThe thalamus serves as a critical relay hub for transmitting peripheral nociceptive information to the cerebral cortex and plays a central role in the sensory, motor, affective, and cognitive dimensions of pain processing. However, the dynamic response patterns of distinct thalamic nuclei during stimulus-pain processing remain poorly understood.
methodsIn this study, fiber photometry was employed to record calcium (Ca
resultsThe results showed that all recorded nuclei exhibited rapid increases in Ca
conclusionsThis study reveals a thalamus-wide functional stratification of neuronal Ca
Indexed as
Calcium SignalingNociceptionThalamic NucleiAnimalsCalciumMaleMiceMice, Inbred C57BLPhysical StimulationTime FactorsCalciumCa2+ signalsdynamic response patternfiber photometrymousenociceptive stimulithalamus
Identifiers
PMID42676057
PMCPMC13531012
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