ArticleThe Journal of international medical research2026
Association between lactate-to-albumin ratio and 28-day all-cause mortality in critically ill patients with chronic kidney disease: A retrospective cohort study from the Medical Information Mart for Intensive Care IV database.
Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectiveThe lactate-to-albumin ratio has been associated with adverse outcomes in various diseases. However, the impact of the lactate-to-albumin ratio on the prognosis of critically ill patients with chronic kidney disease remains unclear. Therefore, this study aimed to investigate the predictive ability of the lactate-to-albumin ratio for 28-day all-cause mortality in critically ill patients with chronic kidney disease.MethodsThis retrospective cohort study included 4271 critically ill patients with chronic kidney disease from the Medical Information Mart for Intensive Care IV database. The exposure factor was the lactate-to-albumin ratio, and the outcome was the 28-day mortality rate. Hazard ratios were computed along with their corresponding 95% confidence intervals using multivariate Cox regression.ResultsMultivariable Cox regression revealed that, compared with the Tertile 1 group, the hazard ratio for 28-day mortality was 1.55 (95% confidence interval: 1.26-1.92,
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