Evidence map›Paper›PMID 42675606›Full record

ReviewAdvanced healthcare materials2026

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Madushani Dahanayake, Md Shahriar A Hossain, Chia-Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Madushani DahanayakeAustralian Institute of Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0003-1354-4683
Md Shahriar A HossainAustralian Institute of Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.
Chia-Hung LiuTMU Research Center of Urology and Kidney and Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Carlos SalomonTranslational Extracellular Vesicles in Obstetrics and Gynae-Oncology Group, Frazer Institute, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Herston, Queensland, Australia.ORCID https://orcid.org/0000-0003-4474-0046
Yusuke YamauchiAustralian Institute of Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0001-7854-927X
Mostafa Kamal MasudAustralian Institute of Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-5346-3135

Funding

Cancer Council QueenslandJST-ERATO Yamauchi Materials Space-Tectonics Project JPMJER2003National Health and Medical Research Council 1195451Next Generation Cancer Research Fellow 2027070
6 · The paper itself

Abstract

Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell-to-cell communication, holding immense potential in diverse biomedical applications. Nanoarchitectonics, a multidisciplinary approach encompassing nanotechnology and biomedicine, offers novel strategies for manipulating EVs at the nanoscale. This review explores the transformative influence of nanoarchitectonics on EVs research, focusing on the current progress in integrating various nanostructures to engineer EVs for enhanced therapeutic and diagnostic capabilities. The application of nanoarchitectonics has led to the fabrication of specialized nanostructures, such as plasmonic, fluorescent, magnetic, carbon-based, and organic-framework-based nanostructures designed explicitly for EVs research. This approach enables the engineering of EVs with improved targeting specificity, cargo loading efficiency, and therapeutic efficacy, thus advancing their potential in precision medicine. The review addresses the opportunities and challenges associated with the convergence of nanoarchitectonics and EVs research, underscoring the necessity for further optimization, rigorous safety assessments, and interdisciplinary collaboration. Finally, the review concludes by discussing the strengths and limitations of the nanoarchitectonics-EVs interface in nanomedicine and therapeutics, providing a strategic roadmap for future advancements in this rapidly evolving field.

Indexed as

Extracellular VesiclesNanostructuresNanotechnologyAnimalsHumansNanomedicineEV‐based diagnosticsEV engineeringextracellular vesiclesnanoarchitectonicsprecision nanomedicine

Identifiers

PMID42675606
PMCPMC13612941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.