ArticleBMC geriatrics2026
Association of surgical timing and early verticalization with 12-month mortality after proximal femur fracture: a prospective cohort study of 641 patients.
Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeProximal femur fractures (PFFs) are associated with high mortality. Both early surgical treatment and early mobilization strategies, including verticalization, are considered key components of patient management. However, the combined association of surgical timing and early verticalization with mortality has not been fully explored.
objectiveTo evaluate the association between the timing of surgery and early verticalization, considered in combination, and 12-month mortality in patients undergoing surgery for proximal femur fracture.
methodsIn this prospective cohort study, 641 patients aged ≥ 65 years underwent surgery for PFF at a Level I Trauma Center between July 2021 and December 2022. Patients were assessed for nutritional status, cognitive status, and comorbidities and categorized by surgical and verticalization timing. Early verticalization was defined as assisted upright positioning within 72 h after surgery. The primary outcome was 12-month mortality. Associations were analyzed using univariate and multivariable logistic regression.
resultsSurgery within 48 h and verticalization within 72 h were associated with lower 12-month mortality (p = 0.007 and p = 0.048). Patients undergoing both early surgery and early verticalization had a lower mortality rate (11.1%), compared to those with delayed surgery and rehabilitation, who had the highest (21.5%). Early verticalization was associated with lower mortality in univariate analysis, but this association was not confirmed after adjustment for confounders. Patients undergoing early verticalization generally had more favorable baseline characteristics.
conclusionsThe combination of early surgical treatment and early verticalization is associated with mortality outcomes in patients with proximal femur fractures. These findings highlight the importance of considering both surgical and rehabilitation timing as part of an integrated care pathway, while acknowledging that causality cannot be established in this observational study. CLINICAL TRIAL NUMBER: not applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.