ArticleDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2026
Patient knowledge and medication safety in chronic warfarin therapy: the roles of adherence, diet, and drug-drug interactions.
Article in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnticoagulant knowledge, medication adherence, time in therapeutic range (TTR), and potential drug-drug interactions (pDDIs) are poorly understood, but they can increase the risk of thromboembolic events, major bleeding, and mortality.
objectivesThis study examined the relationship between oral anticoagulation knowledge and adherence in adults on long-term warfarin therapy, and their associations with TTR, clinical and demographic factors, bleeding risk, and pDDIs.
methodsThis cross-sectional study included adults on chronic warfarin therapy at a university-affiliated cardiology clinic. Turkish versions of the validated Oral Anticoagulation Knowledge (OAK) and Anticoagulant Therapy Adherence Scale (ATAS) assessed oral anticoagulation knowledge and adherence. Clinical, laboratory, and treatment data were obtained from health records, and lifestyle information via patient interviews. pDDIs were evaluated using UpToDate
resultsThe study included 126 adults on warfarin therapy, with a median TTR of 31.9% and 76% of patients below 60%. Patients exhibited moderate oral anticoagulant knowledge and relatively high self-reported adherence scores. A weak positive correlation (ρ = 0.24, p = 0.006) was detected between OAK and ATAS scores, while a negative correlation (ρ=-0.179, p = 0.045) was found between OAK and concurrent medications excluding warfarin. Education and employment status were associated with OAK scores, while the frequency of vitamin K-rich food consumption was associated with ATAS scores. Age and renal impairment were associated with an increased number of concurrent medications excluding warfarin and pDDIs identified by both UpToDate
conclusionAnticoagulation knowledge was weakly associated with adherence to warfarin therapy but not with anticoagulation control. Dietary behaviours, polypharmacy, and pDDIs may influence anticoagulation outcomes, highlighting the need for multifaceted management strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.