ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Observed pre-intervention and non-intervention ventricular growth trajectories in neonates with severe intraventricular hemorrhage and post-hemorrhagic ventricular dilation.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPost-hemorrhagic ventricular dilation (PHVD) after severe intraventricular hemorrhage (SIVH) remains incompletely characterized.
objectiveTo quantify ventricular expansion after SIVH and explore associations with bilateral hemorrhage burden and mortality.
methodsWe retrospectively reviewed 43 neonates with SIVH-associated PHVD cared for in a single NICU from 2010 to 2025. Serial cranial ultrasounds were measured for ventricular index (VI) and anterior horn width (AHW). Post-intervention measurements were censored. An exploratory bilateral hemorrhage-burden score summed maximum right and left IVH grades.
resultsVI and AHW increased significantly with PMA, each at 0.105 mm/day. High composite IVH score (7-8) was associated with faster VI and AHW expansion than low score (3-6), and with higher mortality.
conclusionsVentricular enlargement progressed approximately linearly during observed pre-intervention/non-intervention follow-up. Bilateral hemorrhage-burden scoring may improve risk stratification, but findings are exploratory.
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