Evidence map›Paper›PMID 42675080›Full record

ArticleNature communications2026

Bdelloid rotifers harbor a voltage-gated proton channel with distinct mechanistic features.

Liang Yan, Chiara Boschetti, Liang Hong

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Liang YanDepartment of Medicine, University of Illinois Chicago, Chicago, IL, USA.ORCID 0000-0002-2949-7634
Chiara BoschettiSchool of Biological and Marine Sciences, University of Plymouth, Plymouth, UK.ORCID 0000-0003-4552-3975
Liang HongDepartment of Medicine, University of Illinois Chicago, Chicago, IL, USA. hong2004@uic.edu.ORCID 0000-0003-1101-7046

Funding

Regulation of Voltage-gated Proton ChannelR01GM139991 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HONG, LIANG · 2021 to 2025
$1.6M
Hv1 in Pulmonary HypertensionR01HL174544 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Liang Hong · 2025 to 2026
$1.0M
NHLBI NIH HHS R01 HL174544NIGMS NIH HHS R01 GM139991U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL174544U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R01GM139991
6 · The paper itself

Abstract

Bdelloid rotifers are renowned for their extraordinary resilience. They can survive desiccation and long-term freezing and revive once favorable conditions return. Such remarkable survival abilities suggest that the evolution of specialized molecular adaptations sustain pH homeostasis under extreme environmental stress. In the present study, we identify and functionally characterize an isoform of the voltage-gated proton channel (H

Indexed as

Ion ChannelsRotiferaAmino Acid SequenceAnimalsHumansIon Channel GatingLysineMembrane PotentialsPhylogenyProtonsIon ChannelsLysineProtons

Identifiers

PMID42675080
PMCPMC13530225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.