Evidence map›Paper›PMID 42674797›Full record

Trial reportBMJ open2026

Structural heat adaptation and education in a rural setting of Pakistan: protocol for a randomised controlled trial.

Jai K Das, Syeda Kanza Naqvi, Ana Bonell, Christopher Burman, Joseph Augustin, Shahmeer Qamar, Arjumand Rizvi, Imran Ahmed Chauhadry, Anjum Abbas Naqvi, Muhammad Khan Jamali and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06983483 (Structural Heat Adaptation and Education in Rural Setting), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06983483 narecruitingnot on this map

Structural Heat Adaptation and Education in Rural Setting (SHAPES Trial)

TypeinterventionalSponsorAga Khan UniversityRan2026 to 2028Enrolled7,128ConditionsHeat Illness, Quality of LifeArmsCommunity education and awareness, Participatory local structural and environmental heat mitigation solutions
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jai K DasInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.ORCID 0000-0002-2966-7162
Syeda Kanza NaqviInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.ORCID 0009-0003-9350-0580
Ana BonellMedical Research Council Unit the Gambia at London School of Hygiene and Tropical Medicine, Banjul, Gambia.ORCID 0000-0001-5981-762X
Christopher BurmanThe Bartlett School of Architecture, University College London, London, UK.
Joseph AugustinThe Bartlett School of Architecture, University College London, London, UK.
Shahmeer QamarInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Arjumand RizviInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.ORCID 0000-0003-4553-8130
Imran Ahmed ChauhadryDepartment of Paediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Anjum Abbas NaqviInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Muhammad Khan JamaliInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Hassan NaqviInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Farhana TabassumInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan.
Simon CousensLondon School of Hygiene & Tropical Medicine, London, UK.
Zulfiqar A BhuttaInstitute for Global Health and Development, Aga Khan University, Karachi, Pakistan zulfiqar.bhutta@aku.edu.

Funding

Wellcome TrustWellcome Trust INV-226752/Z/22/Z-53483
6 · The paper itself

Abstract

introductionPakistan is one of the countries most affected by climate change, where peak temperatures in certain areas frequently exceed 40°C. Despite evidence that vernacular designs and behavioural adjustments can reduce indoor temperatures, heat-adaptation efforts remain concentrated in urban or high-resource settings, with limited evidence for vulnerable rural populations in low- and middle-income countries, including Pakistan. METHODS AND ANALYSIS: This trial aims to evaluate the effectiveness of a comprehensive Resilience and Heat Adaptation Bundle (ReHAB) that integrates behavioural and structural interventions to reduce heat-related morbidity and mortality and improve internal ambient conditions in rural settings of Pakistan. This study is a prospective, cluster-randomised trial, comprising 22 clusters allocated to intervention and control arms in a 1:1 ratio. The ReHAB intervention combines community education and awareness with targeted structural improvements, including roof and wall treatments, enhanced shading, improved ventilation, sustainable energy installations and communal outdoor shelters. Health and behavioural data will be collected through household surveys, while wearable devices and environmental sensors will measure individual heat exposure and record indoor and outdoor thermal conditions. ETHICS AND DISSEMINATION: The study has received ethical approval from the Aga Khan University (AKU) (ref: 2025-11559-35625) and National Bioethics Committee (ref: 4-87/NBCR-1065/23/1736). Written informed consent will be obtained from all participants before enrolment. Referral pathways to healthcare facilities will be established to ensure timely management of complications. Findings will be disseminated through peer-reviewed publications, scientific conferences and engagement with policymakers and public health stakeholders. Results will also be shared with participants and communities through meetings and informal sessions to raise awareness and support evidence-based heat adaptation. TRIAL REGISTRATION NUMBER: NCT06983483.

Indexed as

Health EducationHeat Stress DisordersHot TemperatureRural PopulationClimate ChangeHumansPakistanProspective StudiesResearch DesignClimate ChangeCommunity-Based Participatory ResearchPrimary PreventionPUBLIC HEALTHQuality of Life

Identifiers

PMID42674797
PMCPMC13536121

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.