Evidence map›Paper›PMID 42674466›Full record

ReviewArquivos de neuro-psiquiatria2026

Behavioral change: from neurobiology to behavioral-change theories and back - part 1.

Conrado Regis Borges, Fabiano Moulin de Moraes, Marcelo Youngblood, Felipe Chaves Duarte Barros, Nancy Huang, Marcos Christiano Lange

Abstract readReview
In one paragraph

Review in Arquivos de neuro-psiquiatria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Conrado Regis BorgesFaculdade Sírio-Libanês, São Paulo SP, Brazil.ORCID 0000-0003-3220-7746
Fabiano Moulin de MoraesUniversidade Federal de São Paulo, Departamento de Neurologia, São Paulo SP, Brazil.ORCID 0000-0002-4838-2840
Marcelo YoungbloodUniversidade Estadual de Ponta Grossa, Ponta Grossa PR, Brazil.ORCID 0000-0002-4742-7402
Felipe Chaves Duarte BarrosUniversidade Federal de São Paulo, Departamento de Neurologia, São Paulo SP, Brazil.ORCID 0000-0002-4316-9389
Nancy HuangUniversidade de São Paulo, Departamento de Neurologia, São Paulo SP, Brazil.ORCID 0009-0002-8151-3002
Marcos Christiano LangeUniversidade Federal do Paraná, Departamento de Neurologia, Curitiba PR, Brazil.ORCID 0000-0002-0405-7157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Behavioral change remains challenging despite a vast body of evidence linking health behaviors with several health outcomes. Over the past few decades, various health-behavior change theories and techniques have emerged, leading to significant advances in the field. However, although some existing theories provide competent models to structure behavioral-change approaches, they do not provide a unified neurobiological foundation. Objective: To outline the connections between neuroscientific foundations and behavioral-change theories and to provide an overarching neuroscientific perspective. Methods: We conducted a structured narrative review based on data retrieved from major biomedical databases and authoritative neuroscience textbooks to integrate neuroscience data with behavioral-change theories. Results: We describe the neuroscience of behavior from neuroanatomical to neurophysiological mechanisms, emphasizing four brain systems: the hypothalamus, the amygdala, the mesocorticolimbic system, and the prefrontal cortex. Finally, we integrate these mechanisms with a neuroscience-based motivational theory called the Behavior Change Resource Model. Conclusion: The present work integrates established neurobiological knowledge and behavioral-change theories, providing a framework to link theory and health-behavior interventions.

Indexed as

BrainHealth BehaviorPsychological TheoryHumansMotivationNeurobiology

Identifiers

PMID42674466
PMCPMC13529351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.