ArticleCartilage2026
Calcium-Phosphate Subchondroplasty Provides Durable 24-Month Pain Relief and >90% Surgery-free Survivorship for Tibiofemoral Bone Marrow Lesions in Mild-To-Moderate Knee Osteoarthritis: A Prospective Multicenter Study.
Article in Cartilage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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9 authors.
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Abstract
PurposeTo report 24-month clinical outcomes, surgery-free survivorship, and radiological variations after Calcium-Phosphate (CaP) Subchondroplasty (SCP) procedures in patients with symptomatic knee bone marrow lesions (BMLs) in the context of mild-to-moderate knee osteoarthritis (OA).MethodsAdults with tibiofemoral BMLs (Kellgren-Lawrence [KL] 1-3) underwent CaP SCP using a standardized protocol. Prespecified outcomes were KOOS (primary: KOOS Pain), EQ-5D-5L, and pain NRS at baseline, 1, 3, 6, 12, and 24 months; surgery-free survivorship (Kaplan-Meier); and structural status by KL and MOAKS (available-case imaging). Analyses compared time points with paired tests and 95% CIs.ResultsNinety-two knees were treated. KOOS Pain improved from 45.9 ± 14.3 preoperatively to 81.3 ± 18.1 at 24 months (
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