Evidence map›Paper›PMID 42673110›Full record

ArticleChemistry & biodiversity2026

Seasonal Effect on the Chemical Composition of Lippia alba Volatile Chemotypes.

Marcelino Santiago Barroso Neto, Erilene Nayrã Mendonça Brito Lopes, Marcia Ortiz Mayo Marques, Alex Aparecido Rosini Silva, Patricia de Oliveira Carvalho, Alexandra Christine Helena Frankland Sawaya

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcelino Santiago Barroso NetoInstitute of Biology, State University of Campinas, Campinas, Brazil.ORCID https://orcid.org/0000-0002-0152-9219
Erilene Nayrã Mendonça Brito LopesInstitute of Biology, State University of Campinas, Campinas, Brazil.ORCID https://orcid.org/0009-0005-5896-6689
Marcia Ortiz Mayo MarquesAgronomic Institute (IAC), Plant Genetic Resources Center (Phytochemistry), Campinas, SP, Brazil.ORCID https://orcid.org/0000-0001-8270-4308
Alex Aparecido Rosini SilvaLaboratory of Mass Spectrometry MS4Life, São Francisco University, Bragança Paulista, SP, Brazil.ORCID https://orcid.org/0000-0002-6400-5201
Patricia de Oliveira CarvalhoLaboratory of Mass Spectrometry MS4Life, São Francisco University, Bragança Paulista, SP, Brazil.ORCID https://orcid.org/0000-0002-2681-7022
Alexandra Christine Helena Frankland SawayaFaculty of Pharmaceutical Science, State University of Campinas, Campinas, SP, Brazil.ORCID https://orcid.org/0000-0001-7524-6628

Funding

MOMM(FAPESP) #2017/50338-9MOMM(FAPESP) #2018/25812-1.ACHFS(CNPq)#304839/2024-8.
6 · The paper itself

Abstract

Lippia alba (Verbenaceae) is a native Brazilian medicinal species with varied applications, notable for the diversity of volatile chemotypes defined by the major compounds of its essential oil, with fewer studies of its nonvolatile composition. The objective of this work was to perform the chemical characterization via GC-MS and LC-MS of five L. alba individuals, collected during the rainy and dry season. The chromatographic results were analyzed via untargeted metabolomics. Four of the five individuals maintained the same major essential oil composition between the two periods evaluated and each volatile chemotype presented distinct major compounds. The nonvolatile composition, however, was similar for the five L. alba individuals. Some volatile and nonvolatile compounds varied between seasons, demonstrating a discrete effect of the environment on their chemical composition. These results are fundamental for the medicinal application and quality control of this species.

Indexed as

LippiaOils, VolatileSeasonsBrazilChromatography, LiquidGas Chromatography-Mass SpectrometryOils, Volatilechromatographyessential oilhydroethanolic extractmedicinal plantsmetabolomics

Identifiers

PMID42673110
PMCPMC13529227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.