Evidence map›Paper›PMID 42673109›Full record

ArticleChemistry & biodiversity2026

Metabolomic Characterization of 16 Malpighiaceae Species From Brazilian Biomes by UHPLC-MS/MS and PCA.

Jaqueline Munise Guimarães da Silva, Grazielle Jesus Dos Santos, Rafael Felipe de Almeida, Maria Luiza Zeraik

Abstract read
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jaqueline Munise Guimarães da SilvaLaboratory of Phytochemistry and Biomolecules, Department of Chemistry, State University of Londrina (UEL), Londrina, Paraná, Brazil.ORCID https://orcid.org/0000-0002-1482-0195
Grazielle Jesus Dos SantosLaboratory of Phytochemistry and Biomolecules, Department of Chemistry, State University of Londrina (UEL), Londrina, Paraná, Brazil.ORCID https://orcid.org/0000-0002-8699-2033
Rafael Felipe de AlmeidaC.E. Moss Herbarium, School of Animal, Plant and Environment, University of Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-9562-9287
Maria Luiza ZeraikLaboratory of Phytochemistry and Biomolecules, Department of Chemistry, State University of Londrina (UEL), Londrina, Paraná, Brazil.ORCID https://orcid.org/0000-0002-0559-8502

Funding

CNPq 88887 850027/2023-0Coordenação de Aperfeiçoamento de Pessoal de Nivel Superior
6 · The paper itself

Abstract

The Malpighiaceae family comprises approximately 1,500 species distributed across tropical and subtropical regions and is recognized as a source of bioactive secondary metabolites. However, the metabolomic composition of many species remains poorly characterized. Therefore, this study aimed to characterize and compare the metabolomic profiles of 16 Malpighiaceae species collected from four Brazilian biomes (Amazon Rainforest, Atlantic Forest, Caatinga, and Cerrado). Hydroethanolic leaf extracts were analyzed by ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) and chemometric tools. Principal component analysis (PCA) was applied to investigate metabolomic similarities and differences among species. Fifty metabolites were annotated, mainly flavonoids, anthocyanins, tannins, and phenolic acids, demonstrating the remarkable chemodiversity of the family. Multivariate analysis identified discriminant metabolites, including hexadecanoyl glycerol, quercetin-O-glycoside, epigallocatechin, hydroxyflavanone, isorhamnetin galactoside, ferulic acid, and quercetin-3-O-deoxyhexosyl-pentoside. The results revealed substantial metabolomic variability among species occurring within the same biome and highlighted the phytochemical diversity of Malpighiaceae.

Indexed as

MalpighiaceaeMetabolomicsPlant ExtractsAnthocyaninsBrazilChromatography, High Pressure LiquidFlavonoidsPlant LeavesPrincipal Component AnalysisTandem Mass SpectrometryAnthocyaninsFlavonoidsPlant Extractschemometricsmass spectrometryprincipal component analysissecondary metabolitesuntargeted metabolomics

Identifiers

PMID42673109
PMCPMC13529236

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.