Evidence map›Paper›PMID 42673107›Full record

ArticleChembiochem : a European journal of chemical biology2026

Single-Residue Substitution of Opicalcin1 Enhances Cellular Uptake but Reduces Ca

Shumin Wang, Xiaoyu Hua, Xiaofen Ma, Lianbo Wang, Jianguo Wang, Hao Liu, Fei Nie, Yangfei Zhao, Qiuming Zhou, Héctor H Valdivia and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Single-Residue Substitution of Opicalcin1 Enhances Cellular Uptake but Reduces CaChembiochem : a European journal of chemical biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shumin WangCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, China.
Xiaoyu HuaFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Xiaofen MaSchool of Pharmacy, Xinjiang Medical University, Xinjiang, China.
Lianbo WangCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, China.
Jianguo WangCollege of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Hao LiuSchool of Life Sciences, Liaoning Normal University, Dalian, China.
Fei NieFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Yangfei ZhaoCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, China.
Qiuming ZhouFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Héctor H ValdiviaDepartment of Medicine and Cardiovascular Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0003-1231-6267
Liang XiaoFaculty of Naval Medicine, Naval Medical University, Shanghai, China.
Jinming WangCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, China.ORCID https://orcid.org/0009-0001-8712-7316

Funding

National Key Research and 420 Development Programme of China 2023YFE0117800
6 · The paper itself

Abstract

The Calcin family comprises scorpion venom-derived peptides with cell-penetrating activity and reported modulatory effects on RyR-associated Ca

Indexed as

CalciumCalcium-Binding ProteinsCell-Penetrating PeptidesScorpion VenomsAmino Acid SequenceAnimalsHumansRyanodine Receptor Calcium Release ChannelStructure-Activity RelationshipCalciumCalcium-Binding ProteinsCell-Penetrating PeptidesRyanodine Receptor Calcium Release ChannelScorpion VenomsCa2+cell‐penetrating peptidemolecular dockingOpicalcin1ryanodine receptors

Identifiers

PMID42673107
PMCPMC13529225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.