Evidence map›Paper›PMID 42672862›Full record

ArticleChemistry & biodiversity2026

Sesquiterpene-Rich Essential Oil From Magnolia officinalis Stem Bark: Chemical Composition, Biological Activities, and In Silico Approach.

Nguyen Thi Kim Thanh, Phan Hong Minh, Huynh Thi Ngoc Ni, Tran Quang Hai, Le The Hoai, Le Ba Vinh, Pham Minh Quan, Nguyen Dinh Luyen, Ninh The Son

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nguyen Thi Kim ThanhFaculty of Biology, University of Science, Vietnam National University (VNU), Hanoi, Vietnam.
Phan Hong MinhDepartment of Pharmacology, University of Medicine and Pharmacy, Vietnam National University (VNU), Hanoi, Vietnam.
Huynh Thi Ngoc NiFaculty of Education, Ha Tinh University, Cam Binh, Hatinh, Vietnam.
Tran Quang HaiFaculty of Chemical Technology, Hanoi University of Industry, Hanoi, Vietnam.
Le The HoaiFaculty of Chemical Technology, Hanoi University of Industry, Hanoi, Vietnam.
Le Ba VinhFaculty of Medicine and Pharmacy, Yersin University of Da Lat, Lamdong, Vietnam.
Pham Minh QuanInstitute of Chemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.ORCID https://orcid.org/0000-0001-6922-1627
Nguyen Dinh LuyenInstitute of Chemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.ORCID https://orcid.org/0000-0003-2948-6385
Ninh The SonInstitute of Chemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.ORCID https://orcid.org/0000-0002-2413-7496

Funding

Vietnam National Foundation for Science and Technology Development (NAFOSTED) 108.05-2025.03
6 · The paper itself

Abstract

The stem bark essential oil of Magnolia officinalis (M. officinalis) Rehder & E.H. Wilson was investigated for its chemical composition, biological activities, and in silico interactions. From the GC-FID/MS analysis, the sample was dominated by sesquiterpene hydrocarbons (85.38% ± 0.04%). The major constituents were (E)-caryophyllene (21.69% ± 0.020%), α-selinene (10.13% ± 0.016%), (Z)-β-farnesene (7.07% ± 0.011%), β-selinene (6.81% ± 0.006%), γ-muurolene (6.15% ± 0.008%), α-humulene (6.13% ± 0.007%), and δ-cadinene (5.26% ± 0.006%). Remarkably, this is the first report demonstrating the α-glucosidase inhibitory activity of M. officinalis stem bark essential oil, which exhibited significant activity (IC

Indexed as

Anti-Bacterial AgentsAntineoplastic Agents, PhytogenicGlycoside Hydrolase InhibitorsMagnoliaOils, VolatilePlant BarkSesquiterpenesalpha-GlucosidasesAntioxidantsBiphenyl CompoundsHumansMicrobial Sensitivity TestsMolecular Docking SimulationPicratesPlant Stemsalpha-GlucosidasesAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicAntioxidantsBiphenyl CompoundsGlycoside Hydrolase InhibitorsOils, VolatilePicratesSesquiterpenesbiological activityessential oilin silicoMagnoliaceaeMagnolia officinalis

Identifiers

PMID42672862
PMCPMC13529237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.