Evidence map›Paper›PMID 42671985›Full record

ArticleMolecular nutrition & food research2026

Plant-Based α-Linolenic Acid as a Superior Nutraceutical to Modulates Apoptosis, Hypoxic Signaling, and Lipid Metabolic Pathway in Breast Cancer: A Comparative Preclinical Study.

Anurag Kumar, Pratibha Verma, Nikam Siddhant Rahul, Gaurav Kaithwas

Abstract readComparative Study
In one paragraph

Article in Molecular nutrition & food research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anurag KumarDepartment of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow, Uttar Pradesh, India.
Pratibha VermaDepartment of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow, Uttar Pradesh, India.
Nikam Siddhant RahulDepartment of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow, Uttar Pradesh, India.
Gaurav KaithwasDepartment of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow, Uttar Pradesh, India.

Funding

an extramural researchMinistry of Food Processing Industries (MoFPI), Government of IndiaMinistry's headquarters in New Delhisanctioned under the Research and Development Scheme Q-11/32/2018-R&D
6 · The paper itself

Abstract

In this study, we investigated and compared the anticarcinogenic efficacy of plant-derived α-linolenic acid (P-ALA) and marine-derived α-linolenic acid (M-ALA) using MCF-7 breast cancer cell line and mammary gland carcinoma model induced by N-methyl-N-nitrosourea (MNU). In vitro MTT assessment on ER+ MCF-7 cells exhibited significant cell viability with P-ALA (IC

Indexed as

alpha-Linolenic AcidApoptosisBreast NeoplasmsDietary SupplementsLipid MetabolismAnimalsCell SurvivalFemaleHumansMCF-7 CellsSignal Transductionalpha-Linolenic Acidapoptosisbreast cancerlipid profileplant‐derived therapeuticsα‐linolenic acid

Identifiers

PMID42671985
PMCPMC13528968

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.