Evidence map›Paper›PMID 42671725›Full record

SynthesisJournal of robotic surgery2026

Robotic-assisted endoscopic submucosal dissection for superficial gastrointestinal neoplasms: a bayesian meta-analysis & systematic review.

Ashesh Das, Meenakshi Reddy Yathindra, Mujtaba Moazzam, Swaraj Paul, Noorin Riya Tharupeedikayil Sageer, Ritwik Roy, Subhadip Ganguly, Dinesh Babu Sivakumar, Aman Bakhsh, Riyakumari Patel and 1 more

Abstract readSystematic ReviewMeta-Analysis
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In one paragraph

Synthesis in Journal of robotic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ashesh DasIndependent researcher, Department of Gastroenterology, Mayo Clinic, Rochester, MN, USA. das.ashesh@mayo.edu.
Meenakshi Reddy YathindraDepartment of Gastroenterology, NYMC-Roxborough Memorial Hospital, Philadelphia, PA, USA.
Mujtaba MoazzamCorewell Health, Royal Oak, MI, USA.
Swaraj PaulDepartment of Gastroenterology, Chettinad Hospital and Research Institute, Chennai, India.
Noorin Riya Tharupeedikayil SageerDepartment of Gastroenterology, All India Institute of Medical Sciences, Patna, India.
Ritwik RoyDepartment of Gastroenterology, Jalalabad Ragib Rabeya Medical College and Hospital, Sylhet, Bangladesh.
Subhadip GangulyDepartment of Gastroenterology, V.N. Karazin, Kharkiv National University, Kharkiv, Ukraine.
Dinesh Babu SivakumarDepartment of Gastroenterology, All India Institute of Medical Sciences, Patna, India.
Aman BakhshNetaji Subhash Chandra Bose Medical College, Jabalpur, India.
Riyakumari PatelDepartment of Gastroenterology, Surat Municipal Institute of Medical Education & Research, Surat, Gujarat, India.
Faiza KhalidSheikh Zayed Medical College, Rahim Yar Khan, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Superficial gastrointestinal (GI) neoplasms pose a significant global health burden, with endoscopic submucosal dissection (ESD) as the gold standard for curative resection. However, conventional ESD (C-ESD) is technically challenging, with prolonged procedure times and higher complication risks. Robotic-assisted ESD (R-ESD) offers enhanced precision and safety, but evidence is limited. To evaluate the efficacy and safety of R-ESD using a Bayesian single-arm Meta-analysis. Systematic review and Bayesian single-arm meta-analysis. Following PRISMA guidelines and PROSPERO registration (CRD420251273787), we conducted a systematic review and Bayesian single-arm meta-analysis of randomized/nonrandomized comparative and single-arm studies on R-ESD for superficial GI neoplasms. Searches spanned MEDLINE, Embase, Scopus, and others through December 2025. Primary outcomes: en-bloc and R0 resection rates. Secondary outcomes: procedure time, perforation, bleeding. Bayesian random-effects models used non-informative priors; analyses in R with the brms package. Risk of bias was assessed via RoB 2 and NOS; certainty via GRADE. Five studies (183 lesions) were included. Frequentist pooled en-bloc resection rate: 98.2% (95% CI: 0.916-0.996, I2 = 0%); R0: 96.8% (95% CI: 0.759-0.997, I2 = 47.8%). Bayesian medians: en-bloc 93.4% (95% CrI: 0.856-0.971); R0 90.0% (95% CrI: 0.798-0.957). 77.6 min (95% CI: 45.0-110.3, I2 = 99%); perforation: 1.2% (95% CI: 0.002-0.077, I2 = 0%); bleeding: 10.6% (95% CI: 0.019-0.416, I2 = 30.8%). Evidence certainty:low. R-ESD demonstrates promising efficacy and safety, but current evidence is limited to small, mostly non-comparative studies. Larger comparative trials are required before definitive conclusions can be made.

Indexed as

Endoscopic Mucosal ResectionGastrointestinal NeoplasmsRobotic Surgical ProceduresBayes TheoremHumansOperative TimeBayesian meta-analysisEndoscopic roboticsESDGastrointestinal neoplasmsRobotic-assisted endoscopic submucosal dissection

Identifiers

PMID42671725

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.