Evidence map›Paper›PMID 42671641›Full record

ArticleInternational ophthalmology2026

Objective AS-OCT measurements of tear meniscus parameters following upper eyelid blepharoplasty.

Ramzi M Alameddine, Noura Wahoud, Hussein Baalbaki, Ali Hmede, Reem Amine, Ali Khalil, Martine El Bejjani, Sara Mansour, Massoud Khraiche

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Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ramzi M AlameddineDepartment of Ophthalmology, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut, Lebanon. ramzi.alameddine@aub.edu.lb.
Noura WahoudDepartment of Ophthalmology, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut, Lebanon.
Hussein BaalbakiDepartment of Ophthalmology, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut, Lebanon.
Ali HmedeDepartment of Ophthalmology, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut, Lebanon.
Reem AmineDepartment of Ophthalmology, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut, Lebanon.
Ali KhalilDepartment of Ophthalmology, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut, Lebanon.
Martine El BejjaniClinical Research Institute, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Sara MansourClinical Research Institute, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Massoud KhraicheDepartment of Biomedical Engineering, American University of Beirut Medical Center, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effect of upper eyelid blepharoplasty on objective ocular surface and tear meniscus parameters, including novel measurements obtained by anterior segment optical coherence tomography (AS-OCT).

methodsA prospective, single-center study was conducted on 102 eyes (51 patients) undergoing upper eyelid blepharoplasty. Outcome measures included the Ocular Surface Disease Index (OSDI), Schirmer testing, and AS-OCT parameters: non-invasive anterior surface-tear breakup time (AS-TBUT), tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA). Changes over time were analyzed using mixed-effects statistical models.

resultsWithin the first 10 days postoperatively, significant increases were observed in OSDI (β = 3.035; 95% CI 1.210-4.860; P = 0.001), TMD (Β = 69.717, p = 0.004), and TMA (Β = 37,377.94, p = 0.005). TMH showed a non-significant trend toward increase (p = 0.098). No statistically significant changes were detected in Schirmer testing or AS-TBUT. At > 10 to ≤ 30 days, > 30 to ≤ 50 days, and > 50 days, no statistically significant differences from the preoperative assessment were detected.

conclusionUpper eyelid blepharoplasty was associated with early increases in TMD, TMA, and OSDI, reflecting increased tear volume and ocular surface symptoms. No statistically significant changes were detected in tear-film stability or aqueous tear production. At later time points, no statistically significant differences from baseline were detected.

Indexed as

BlepharoplastyDry Eye SyndromesEyelidsTearsTomography, Optical CoherenceAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative PeriodProspective StudiesBlepharoplastyLacrimalOcular surfaceTear meniscus parameters

Identifiers

PMID42671641

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.