ArticleWiener klinische Wochenschrift2026
Exercise-based early cardiac rehabilitation after percutaneous coronary intervention for acute myocardial infarction : A randomized pilot trial.
Article in Wiener klinische Wochenschrift, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo evaluate the effects of exercise-based early cardiac rehabilitation (EB-ECR) initiated within 24 h after acute myocardial infarction (AMI) and percutaneous coronary intervention (PCI) on cardiac function and functional capacity at 12 weeks.
designSingle-center, parallel-group randomized pilot trial.
settinga tertiary hospital with dedicated cardiac rehabilitation services.
participantsclinically stable AMI patients within 24 h of successful PCI.
interventionsparticipants were randomized 1:1 to EB-ECR, consisting of an individualized, phased rehabilitation program initiated in-hospital and continued postdischarge, or usual care without structured cardiac rehabilitation (NO-CR).
main outcome measuresPrimary endpoints included left ventricular ejection fraction (LVEF), peak oxygen uptake (VO
resultsIn this study 24 participants were randomized (EB-ECR n = 12; NO-CR n = 12). Compared to NO-CR, baseline-adjusted analyses favored EB-ECR: LVEF was higher by 2.8% (95% confidence interval, CI 0.9-4.8%; p = 0.007), VO
conclusionInitiation of EB-ECR within 24 h post-PCI was associated with higher LVEF, greater exercise capacity, and lower BNP at 12 weeks without an observed excess of short-term major adverse cardiovascular events. These findings support the feasibility and potential efficacy of early structured rehabilitation after AMI and PCI.
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