Evidence map›Paper›PMID 42671191›Full record

ArticleJournal of virology2026

Pathogenesis and neurotropism of a contemporary Powassan virus lineage II strain in mice.

Samantha J Courtney, Emily N Gallichotte, Emma Nilsson, Chasity E Trammell, Kate X Kimball, Anna C Fagre, Allison C Vilander, Anna K Överby, Gregory D Ebel

Abstract read
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Samantha J CourtneyDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0001-9277-2937
Emily N GallichotteDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Emma NilssonDepartment of Clinical Microbiology, Umeå University, Umeå, Sweden.
Chasity E TrammellDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Kate X KimballDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Anna C FagreDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Allison C VilanderDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Anna K ÖverbyDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0001-6553-0940
Gregory D EbelDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID 0000-0002-4458-9959

Funding

Emergence of tick borne encephalitis in North AmericaR01AI137424 · NIAID · TUFTS UNIVERSITY BOSTON · PI EBEL, GREGORY DAVID, TELFORD, SAM R · 2019 to 2023
$2.5M
CSU Infectious Disease Research and Response Training ProgramT32AI162691 · NIAID · COLORADO STATE UNIVERSITY · PI DEAN, GREGG A · 2021 to 2025
$2.1M
National Institute of Allergy and Infectious Diseases R01AI137424National Institute of Allergy and Infectious Diseases T32AI162691NIAID NIH HHS R01 AI137424NIAID NIH HHS T32 AI162691Swedish Research Council 2020-06224
6 · The paper itself

Abstract

Powassan virus (POWV) is an emerging tick-borne flavivirus that can cause neurologic disease in humans. POWV exhibits substantial genetic and phenotypic diversity, including marked variability in replication

Indexed as

Encephalitis, Tick-BorneEncephalitis Viruses, Tick-BorneViral TropismAmino Acid SubstitutionAnimalsBrainDisease Models, AnimalFemaleMiceRNA, ViralSpleenViral Envelope ProteinsViral Nonstructural ProteinsVirus ReplicationRNA, ViralViral Envelope ProteinsViral Nonstructural ProteinsneuroinvasionpathogenesisPowassan virustick-borne flavivirusviral determinants

Identifiers

PMID42671191
PMCPMC13595934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.