Evidence map›Paper›PMID 42671189›Full record

ArticleMicrobiology resource announcements2026

DiMER: a modular framework for replacing uninformative annotations in protein datasets.

Ellis L Torrance, Kelly P Williams, Joseph S Schoeniger, Catherine M Mageeney

Abstract read
In one paragraph

Article in Microbiology resource announcements, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ellis L TorranceSystems Biology Department, Sandia National Laboratories, Livermore, California, USA.
Kelly P WilliamsSystems Biology Department, Sandia National Laboratories, Livermore, California, USA.ORCID 0000-0002-2606-9562
Joseph S SchoenigerBiological, Radiation, and Signature Science, Technology, & Engineering Center, Sandia National Laboratories, Livermore, California, USA.ORCID 0000-0002-2719-7435
Catherine M MageeneyBiotechnology & Bioengineering Department, Sandia National Laboratories, Livermore, California, USA.ORCID 0000-0001-7969-1622

Funding

Biological and Environmental Research 24-026159
6 · The paper itself

Abstract

DiMER (https://github.com/sandialabs/DiMER) is a modular Python framework using user-provided BLAST and HMM databases to assign annotations while avoiding placeholders (e.g., hypothetical protein). DiMER was applied to a curated list of gold standard mobile genetic elements and increased functional annotations by 24% (49 to 73%).

Indexed as

annotationmicrobesmobile elementsphage

Identifiers

PMID42671189
PMCPMC13688798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.