ArticleClinical and experimental dental research2026
Antibiofilm Activity of a Thermoformable Material Loaded With Essential Oil Solution.
Article in Clinical and experimental dental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundInterest in antimicrobial surfaces for dental devices, such as aligners and brackets, is growing. These surfaces are designed to retard biofilm formation. One approach is to load essential oils (EOs) into the material. The focus of this study was the antibacterial, anti-biofilm, and anti-inflammatory activities of an EO solution.
methodsThe EO solution contained cinnamaldehyde, methyl salicylate, eucalyptol, limonene, and trans-anethole dissolved in distilled water (dH
resultsThe EO solution clearly inhibited bacterial growth. However, the basic solution also acted as a growth inhibitor at higher concentrations. The EO solution reduced the metabolic activity of the formed biofilm. In addition, the basic solution decreased biofilm mass and colony-forming unit counts. The basic solution was not inferior to CHX on the reference material. However, only the basic solution, not the EO solution, suppressed the release of IL-8 from GF when stimulated with bacteria.
conclusionApplying essential oils (EOs) to surfaces may be an effective way to inhibit biofilm formation. The basic solution, which is polyglyceryl-laurate-based, exhibits anti-biofilm and anti-inflammatory properties. Further in vitro research should aim to gain a deeper understanding of the solubilizer's mechanisms and optimize the composition of the added essential oils before testing in clinical trials.
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