Evidence map›Paper›PMID 42670038›Full record

ArticleMicrobiologyOpen2026

The Mycorrhizal Fungal Species Funneliformis mosseae Reshapes Rhizosphere Microbial Metabolic Pathways of Soybeans Under Tetracycline Stress.

Chao Yang, Baiyan Cai, Harry Lye Hin Chong, Juan Li, Linghui Li, Jean Wan Hong Yong, Khim Phin Chong

Abstract read
In one paragraph

Article in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chao YangDepartment of Science, Heihe University, Heihe, China.ORCID https://orcid.org/0000-0001-6049-2105
Baiyan CaiEngineering Research Center of Agricultural Microbiology Technology, College of Heilongjiang Province & School of Life Sciences, Heilongjiang University, Harbin, China.ORCID https://orcid.org/0000-0003-1362-398X
Harry Lye Hin ChongBiophysics Research Group, Faculty of Science and Technology, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu, Sabah, Malaysia.
Juan LiDepartment of Science, Heihe University, Heihe, China.
Linghui LiDepartment of Science, Heihe University, Heihe, China.
Jean Wan Hong YongDepartment of Biosystems and Technology, Swedish University of Agricultural Sciences, Alnarp, Sweden.ORCID https://orcid.org/0000-0003-3325-8254
Khim Phin ChongBiophysics Research Group, Faculty of Science and Technology, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu, Sabah, Malaysia.ORCID https://orcid.org/0000-0002-5143-7283

Funding

Basic scientific research projects of colleges and universities in Heilongjiang Province 2024-KYYWF-0905Heilongjiang Province Ecological Environmental Protection Scientific Research Project 2022 HST2022TR002National Natural Science Foundation of China 3197180012
6 · The paper itself

Abstract

Studies have demonstrated that arbuscular mycorrhizal fungi (AMF) can alter the rhizosphere microbial communities during exposure to tetracycline, thereby alleviating the adverse effects of antibiotics. We hypothesized that Funneliformis mosseae (F. mosseae) reshapes soil metabolite composition and associated-microbial pathways under tetracycline stress and that these metabolite changes are associated with the rhizosphere microbial communities. To test this hypothesis, microbiological profiling with metabolomics approaches were carried out to investigate how AMF reshape rhizosphere metabolite profiles in soybeans undergoing tetracycline stress. Specifically, inoculation with F. mosseae altered the soil metabolite profiles, with 34 differential metabolites identified, including 14 upregulated and 20 downregulated compounds, mainly amino acids, sugar phosphates, fatty acids, polyphenols, triterpenes, and heterocyclic compounds. In addition, 19 differential metabolic pathways were identified and classified into four metabolic clusters: polyunsaturated fatty acids and oxidative stress-related metabolism, carbon source and energy metabolism, amino acid and sulfur-containing metabolism, and secondary metabolism and defense responses. The correlation analysis between soil metabolites and published rhizosphere microbial data revealed 14 metabolites, including Trehalose-6-phosphate, increased with bacterial abundance, while five metabolites decreased; similarly, four metabolites increased and three decreased with fungal abundance. Correlation network analysis further indicated that 16 differential metabolites were significantly associated with 8 differential bacterial genera, and 12 differential metabolites were significantly associated with six fungal genera. Overall, our findings demonstrated that F. mosseae plays a crucial role in regulating microbial metabolism and interactions in tetracycline-contaminated soils, providing valuable insights into the mechanisms by which AMF alleviate tetracycline-induced stress in soils.

Indexed as

Anti-Bacterial AgentsGlomeromycotaGlycine maxMetabolic Networks and PathwaysMycorrhizaeRhizosphereTetracyclineFungiMetabolomeMetabolomicsSoilSoil MicrobiologyStress, PhysiologicalAnti-Bacterial AgentsSoilTetracyclinearbuscular mycorrhizal fungicorrelation network analysismicrobial interactionsrhizosphere metabolomesoil metabolomics

Identifiers

PMID42670038
PMCPMC13527221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.