Evidence map›Paper›PMID 42669874›Full record

ArticleCNS neuroscience & therapeutics2026

Whole-Brain Monosynaptic Inputs and Outputs of Corticotropin-Releasing Hormone Neurons of the Paraventricular Nucleus of the Hypothalamus in Male Mice.

Ziteng Yue, Danyang Zhao, Xinxin Chen, Yousheng Zhang, Heng Zhang, Yinchang Wang, Yuhang Liu, Yuxin Yang, Can Geng, Yimeng Song and 2 more

Abstract read
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In one paragraph

Article in CNS neuroscience & therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Ziteng YueDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0009-0001-4089-1333
Danyang ZhaoDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Xinxin ChenDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Yousheng ZhangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0009-0008-4998-668X
Heng ZhangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Yinchang WangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Yuhang LiuDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Yuxin YangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Can GengDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Yimeng SongDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.
Xiaoyi WangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0009-0006-8410-9717
Sheng WangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0000-0001-9579-4808

Funding

China Postdoctoral Science Foundation 2025M782604Hebei Medical University Natural Science Foundation for Outstanding PhD Student YBKJ202502National Natural Science Foundation of China U23A20431Natural Science Foundation of Hebei Province for Innovative Research Group Project H2025206897Postdoctoral Science Foundation of Hebei Medical University
6 · The paper itself

Abstract

objectiveThe paraventricular nucleus of the hypothalamus (PVN) is a central hub integrating neuroendocrine, autonomic, and behavioral responses. Corticotropin-releasing hormone (CRH) neurons in the PVN (PVN

methodsUsing Cre-dependent modified rabies virus for retrograde monosynaptic tracing and adeno-associated viruses for anterograde tracing in CRH-Cre mice, we systematically mapped the whole-brain inputs and outputs of PVN

resultsPVN

conclusionThis study establishes a comprehensive whole-brain monosynaptic input-output atlas of PVN

Indexed as

BrainCorticotropin-Releasing HormoneNeuronsParaventricular Hypothalamic NucleusSynapsesAnimalsMaleMiceMice, Inbred C57BLMice, TransgenicNeural PathwaysCorticotropin-Releasing Hormonecorticotropin‐releasing hormoneinputsoutputsparaventricular nucleus of the hypothalamusstress

Identifiers

PMID42669874
PMCPMC13527161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.