ArticleNature communications2026
The m⁶A reader YTHDF2 regulates mRNA transport and axon outgrowth in developing neurons.
Bonsang Koo, Ajeet Kumar, Huiseon Hwang, Minyeong Park, Sung-Min Lee, Sung Ho Boo, Ki-Heon Lee, Ji-Hoon Moon, Jaewon Yang, Chan-Woo Park and 10 more
Abstract read
In one paragraphArticle in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
20 authors.
Bonsang Koo *Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID 0000-0002-1575-4038 Ajeet Kumar *Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Huiseon Hwang *Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID 0009-0001-2957-0870 Minyeong ParkDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Sung-Min LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID 0009-0000-7172-7459 Sung Ho BooKAIST InnoCORE AI-CRED Institute, KAIST, Daejeon, Republic of Korea.
Ki-Heon LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Ji-Hoon MoonDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Jaewon YangDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID 0000-0002-3795-3150 Chan-Woo ParkDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Saebom LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Woo-Il KimCTX Co., Ltd., Seoul, Republic of Korea.
Eunji ChoNeurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu, Republic of Korea.ORCID 0000-0002-9589-3643 Hagyeong LeeNeurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu, Republic of Korea.
Jae-Sung WooCenter for Biomolecular and Cellular Structure, Institute for Basic Science, Daejeon, Republic of Korea.ORCID 0000-0001-9163-3433 Jong Hyuk YoonNeurodegenerative Diseases Research Group, Korea Brain Research Institute, Daegu, Republic of Korea.ORCID 0000-0002-4090-3832 Yoon Ki KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID 0000-0003-1303-072X Ki-Jun YoonDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea. kijunyoon@kaist.ac.kr.ORCID 0000-0003-2985-2541 Funding
National Research Foundation of Korea (NRF) 2020M3A9E403967022National Research Foundation of Korea (NRF) RS-2024-00332454National Research Foundation of Korea (NRF) RS-2024-00440778
6 · The paper itselfAbstract
Proper nervous system development is critical for brain function, and deficits in neural development are implicated in many brain disorders. Neurons are distinctly polarized cells where mRNA can be transported to distal structures like axons and dendrites. Recent discoveries of widespread mRNA chemical modifications raise the question of their post-transcriptional regulatory role in brain development and function. N
Indexed as
AxonsNerve Tissue ProteinsNeuronal OutgrowthNeuronsRNA-Binding ProteinsRNA, MessengerAdenosineAnimalsEpitranscriptomeMethyltransferasesMiceNeurodevelopmentNeurogenesisRNA MethylationRNA TransportAdenosineMethyltransferasesMettl14 protein, mouseNerve Tissue ProteinsN-methyladenosineRNA-Binding ProteinsRNA, MessengerYTHDF2 protein, mouse
Identifiers
PMID42669734
PMCPMC13526771
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