ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026
Glass ionomer cement in incudostapedial rebridging ossiculoplasty: A systematic review and meta-analysis.
Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
purposeTo evaluate the hearing outcomes and surgical success of glass ionomer cement (GIC) in incudostapedial rebridging ossiculoplasty (ISRO) in patients with different middle ear pathologies.
methodsA systematic literature review was conducted on Medline (via PubMed), the Cochrane Database, and Scopus from database inception to July 4, 2025. Two independent authors reviewed selected studies assessing the short-, middle-, or long-term tone audiometry results, the air-bone gap (ABG) closure percentage, and cement failure outcomes. The review adhered to the PRISMA reporting standards. Meta-analysis calculated the mean differences between post- and pre-operative pure-tone audiometry values (pooled estimates and 95% confidence intervals). ABG closure was analyzed with a meta-analysis of proportions applying a logit transformation.
resultsTwenty-four studies (17 observational cohort and 8 observational case-series) were included in this review, encompassing 749 patients receiving ISRO. All studies included provided preoperative and postoperative hearing outcomes. Nineteen studies reported outcomes regarding ABG closure < 20 dB, 10 regarding closure < 10 dB, 7 regarding cement failure, and 8 regarding postoperative adverse events following ISRO. A pooled mean change in ABG values of - 16.54 dB (95% CI - 20.61 to - 12.47) and in air conduction values of - 18.01 dB (95% CI - 20.86 to - 15.17) was achieved from pre- to post-operative middle-term outcomes. The pooled success rate was 77.3% for ABG < 20 dB (95% CI 71.9-82.0), and 52.7% (95% CI 41.3-63.8) for ABG < 10 dB.
conclusionIncudostapedial rebridging ossiculoplasty (ISRO) appears to be a reliable solution with good hearing outcomes 1 to 3 years postoperatively.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.