Evidence map›Paper›PMID 42669617›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

CD9

Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Wenjing Liao *State Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Lijuan Song *State Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Meiqian Xu *State Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Tianhao Liang *Department of Otolaryngology-Head and Neck Surgery, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China.
Yixuan Chen *Department of Basic Science, YuanDong International Academy of Life Sciences, Hong Kong, China.
Gui ChenState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Zaihuan LinState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Huakang DuState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Guofei FengState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Zhiming FengState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Qi ZhangState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Fan PanState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Saixuan YangState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Xinyin ZhangState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Wenxu PengState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Tianlong LiState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Zhuoshen LinState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Yabang ChenState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Jiayi LiuState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Baoxin PengState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Yan LiuDepartment of Otolaryngology-Head and Neck Surgery, The People's Hospital of Kaizhou District, Chongqing, China.
Xing NiuDepartment of Basic Science, YuanDong International Academy of Life Sciences, Hong Kong, China.
Ting LiDepartment of Basic Science, YuanDong International Academy of Life Sciences, Hong Kong, China.
Chengyu HuangDepartment of Basic Science, YuanDong International Academy of Life Sciences, Hong Kong, China.
Ke MoDepartment of Basic Science, YuanDong International Academy of Life Sciences, Hong Kong, China.
Jianlei XieState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.
Yu ZouDepartment of Otolaryngology-Head and Neck Surgery, Guangdong Women and Children Hospital, Guangzhou, Guangdong, China.
Xiaowen ZhangState Key Laboratory of Respiratory Disease, Department of Otolaryngology-Head and Neck Surgery, Loudi Central Hospital, The First Affiliated Hospital of Guangzhou Medical University, Loudi, Hunan, China.ORCID https://orcid.org/0000-0001-5255-8610

Funding

Autonomous Project of State Key Laboratory of Respiratory Disease SKLRD-Z-202205China Postdoctoral Science Foundation 2021M700947Guangzhou Medical Key Discipline Construction Project 2021-2023National Clinical Key Specialty Construction Project 2021-2024
6 · The paper itself

Abstract

Adenoid hypertrophy (AH) is associated with excessive proliferation of germinal center B (GC-B) cells, yet the mechanisms underlying GC regression and termination remain poorly understood. This study used single-cell RNA sequencing (scRNA-seq) to profile the cellular composition of GC-B cells in AH. A unique subset of GC-B cells expressing CD9 was identified through comprehensive scRNA-seq, flow cytometry, and Mass cytometry (CyToF) analyses, with subsequent studies assessing the roles of CD9 and FOXP1 in GC-B cell differentiation and apoptosis pathways. CD9

Indexed as

adenoid hypertrophyCD9FOXP1germinal center B cellTfh cells

Identifiers

PMID42669617
PMCPMC13526695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.