Evidence map›Paper›PMID 42668900›Full record

ArticlemicroPublication biology2026

POC1A colocalizes with POC1B in human and bovine spermatozoa centrioles.

Robert Heizelman, Yash Dixit, Derek Kluczynski, Jenna Bearden, Caitlin Stidam, Zach Madaras, Meghana Perumalla, Lydeyiah Roesner, Waleed Hamdan, Samantha Schon and 4 more

Abstract read
In one paragraph

Article in microPublication biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Robert Heizelman *University of Toledo, Toledo, OH, US.
Yash Dixit *University of Toledo, Toledo, OH, US.
Derek KluczynskiUniversity of Toledo, Toledo, OH, US.
Jenna BeardenUniversity of Toledo, Toledo, OH, US.
Caitlin StidamUniversity of Toledo, Toledo, OH, US.
Zach MadarasUniversity of Toledo, Toledo, OH, US.
Meghana PerumallaUniversity of Toledo, Toledo, OH, US.
Lydeyiah RoesnerUniversity of Toledo, Toledo, OH, US.
Waleed HamdanUniversity of Toledo, Toledo, OH, US.
Samantha SchonUMich, Ann Arbor, MI, US.
Nagalakshmi NadimintyUniversity of Toledo, Toledo, OH, US.
Tariq ShahDepartment of Urology, University of Toledo, Toledo, OH, US.
Puneet SindhwaniDepartment of Urology, University of Toledo, Toledo, OH, US.
Tomer Avidor-ReissDepartment of Urology, University of Toledo, Toledo, OH, US.

Funding

The Role of Rabbit POC1B inSperm CentriolesR15HD110863 · NICHD · UNIVERSITY OF TOLEDO · PI AVIDOR-REISS, TOMER · 2023 to 2023
$452k
NICHD NIH HHS R15 HD110863
6 · The paper itself

Abstract

Infertility impacts one in seven couples globally, with one-third of cases classified as unexplained. One source of unexplained infertility is the spermatozoon centrosome, a subcellular structure composed of two remodeled centrioles (the proximal and distal centrioles) and specialized pericentriolar material, located in the spermatozoon neck. The centrosome functions as the head-neck linker in the spermatozoa. Here, we investigated the localization of the somatic cell centriole lumen protein POC1A using immunofluorescence and confocal microscopy. We found that POC1A localizes to the neck, colocalizing with POC1B, and is present in both the proximal and distal centrioles in both human and bovine spermatozoa.

Identifiers

PMID42668900
PMCPMC13525453

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.