Evidence map›Paper›PMID 42668792›Full record

ArticleSubstance use : research and treatment

Peer Vaped Nicotine Use in Adolescents and Young Adults: Associations With Abstinence and Intervention Adherence During a Quit Attempt.

Meghan A Costello, Bryn Evohr, Vanessa Iroegbulem, Jason Dufour, Kelly Casottana, Corinne Cather, Gladys Pachas, Randi M Schuster, A Eden Evins

Abstract read
In one paragraph

Article in Substance use : research and treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meghan A CostelloDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-9520-4676
Bryn EvohrDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Vanessa IroegbulemDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0009-0000-3979-4360
Jason DufourDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Kelly CasottanaDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0009-0008-3195-8349
Corinne CatherDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-1516-0499
Gladys PachasDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.
Randi M SchusterDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5710-9301
A Eden EvinsDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA.

Funding

Career Development Program in Substance Use and Addiction MedicineK12DA043490 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI A EDEN EVINS, NANCY A RIGOTTI · 2017 to 2026
$4.7M
Research Supplement to Promote Diversity in Health-Related Research: Randomized controlled trial of varenicline for cessation of nicotine vaping in adolescent non-smokersR01DA052583 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI EVINS, A EDEN, SCHUSTER, RANDI MELISSA · 2021 to 2023
$2.2M
NIDA NIH HHS K12 DA043490NIDA NIH HHS R01 DA052583
6 · The paper itself

Abstract

Background: Vaped nicotine use is associated with nicotine dependence, mental health symptoms, and physical health problems in adolescents, and peer nicotine use is a robust predictor of nicotine vaping in adolescents and young adults. Objective: Examine associations between peer nicotine vaping and participant nicotine vaping cessation outcomes or nicotine dependence treatment adherence among adolescents and young adults enrolled in a vaping cessation trial. Design: Exploratory secondary analysis of a 12-week randomized controlled trial with 3-month follow-up. Methods: Participants completed a three arm, 12-week trial of varenicline and counseling, placebo and counseling, or enhanced treatment-as-usual. Participants (N=280; ages 16-25) indicated number of close friends in their broad peer network who use nicotine vapes, and a subset reported on frequency of nicotine vaping among their 10 closest friends as well as frequency of vaping by their best friend. Analyses evaluated the effect of peer vaping on biochemically-verified 7-day nicotine abstinence (end-of-treatment and follow-up) and treatment adherence. Multilevel mixed-effects models accounted for treatment condition. Results: Participants reported a mean of 6.9 ( Conclusion: Peer vaping behavior may be associated with adolescents' capacity to quit vaped nicotine. Interventions that directly address peer network influences may enhance vaping cessation outcomes.

Indexed as

adolescenceintervention trialnicotine vapepeer influencetreatment adherence

Identifiers

PMID42668792
PMCPMC13525276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.