Evidence map›Paper›PMID 42668735›Full record

ReviewGenes & diseases2026

A comprehensive review on apoptotic miRNAs and antagomiRs in breast cancer: Enhancing radio sensitization.

Maryam Najafi-Amiri, Mina Pourhabib-Mamaghani, Seyed Hamid Aghaee-Bakhtiari, Mohammad-Taghi Bahreyni-Toossi, Hosein Azimian

Abstract readReview
In one paragraph

Review in Genes & diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maryam Najafi-AmiriDepartment of Medical Physics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9919191778, Iran.
Mina Pourhabib-MamaghaniDepartment of Medical Physics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9919191778, Iran.
Seyed Hamid Aghaee-BakhtiariDepartment of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9919191778, Iran.
Mohammad-Taghi Bahreyni-ToossiDepartment of Medical Physics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9919191778, Iran.
Hosein AzimianDepartment of Medical Physics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 9919191778, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) is the most fatal cancer in women worldwide, and in spite of progresses in cancer treatment methods, its therapy has remained as a primary health issue. Inadequate apoptosis level is one of the main reasons of radiotherapy and chemotherapy resistance in lots of cancers including BC. Besides, gene therapy is one of new methods which has been proposed and developed in recent decades for various diseases diagnosis and treatment containing cancer. Since changes in miRs level which are one of different types of RNA molecules have been proved in assorted diseases, they are utilized as a gene therapy agent in order to make influence in diverse signaling pathways which are effective in unappealing biological alteration. In lots of studies, miRs' role in apoptosis pathway in combination with radiotherapy, chemotherapy or solely have been investigated. Many miRNAs and anti-miRNAs have been demonstrated as radiosensitizers/radioresistance agents and chemosensitisers/chemoresistance agents through apoptosis cell death pathways, and numerous miRs have been introduced as apoptotic regulators and they have a good potential to be radiosensitizers and their role in these pathways must be investigated. In the current review, we have tried to investigate and summarize radiosensitizer and radioresistant miRs and anti-microRNAs (anti-miRs) which have been utilized in BC.

Indexed as

ApoptosisBreast cancermicroRNARadioresistanceRadiosensitivity

Identifiers

PMID42668735
PMCPMC13524867

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.