ArticleInternational journal of cardiology. Congenital heart disease2026
Bovine pericardial versus porcine bioprosthetic valves in pulmonary position for adult congenital heart disease: A three-center, retrospective, propensity-weighted analysis of clinical outcomes.
Article in International journal of cardiology. Congenital heart disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction and objective: Adults with congenital heart disease affecting the right ventricular outflow tract often require repeated pulmonary valve replacements (PVR) throughout life, making prosthesis durability a critical determinant of long term outcomes. Bovine pericardial and porcine bioprosthetic valves are the most widely used in surgical PVR, yet comparative durability data remain inconsistent, partly due to reliance on nominal valve size rather than functional parameters. This study aimed to compare long term durability between both valves using indexed effective orifice area (iEOA) and analytic methods focused on prosthesis related performance. Methods: We conducted a retrospective, multicenter observational study including pediatric and adult patients undergoing surgical PVR between 2013 and 2024 at three tertiary hospitals in Spain. The primary endpoint was a composite outcome of all cause mortality, reintervention, and structural valve deterioration. Propensity scores were constructed using clinically selected covariates and applied through inverse probability weighting (IPW). To isolate prosthesis related durability, survival was analysed by Cox regression model with left truncation at 1 year. Results: A total of 231 patients were included (49.4% female; 64.1% with tetralogy of Fallot). Overall, 19.0% experienced a MACE during follow up, occurring at a median of 4.8 years after the truncation point. After IPW adjustment, baseline characteristics were well balanced. In the IPW adjusted Cox regression model, porcine prostheses were associated with a lower hazard of MACE (HR 0.37; 95% CI 0.16-0.83; p = 0.015). Conclusions: When early postoperative events are excluded and baseline differences minimized, porcine bioprostheses exhibit superior mid and long term durability compared with bovine pericardial valves.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.