Evidence map›Paper›PMID 42668590›Full record

ArticleiScience2026

Miscompartmentalization of microbiota-derived TMAO is a reversible driver in autism spectrum disorder.

Jean-Marie Launay, Nicolas Vodovar

Abstract read
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jean-Marie LaunayUniversité Paris Cité and Inserm UMR-S 942 MASCOT, Paris, France.
Nicolas VodovarUniversité Paris Cité and Inserm UMR-S 942 MASCOT, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder. Unlike genetics and gut dysbiosis, ASD appears to be homogeneous when considering tryptophan metabolism. Following these findings, we found that ASD was associated with the miscompartmentalization of the chemical chaperone trimethylamine

Indexed as

autism spectrum disorderbehaviorchaperonemetabolismosmolaritytrimethylamine N-oxide

Identifiers

PMID42668590
PMCPMC13524769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.