Evidence map›Paper›PMID 42668467›Full record

ArticleBioactive materials2027

Supramolecular engineering of fibrinogen into a fibrin matrix with enhanced bioactive properties.

Domenico Laurenza, Fraser L Macrae, Ieva Sapjanskaite, Alex Hartley, Bapan Pramanik, Soraya Padilla-Lopategui, Felicity R A J Rose, Robert A S Ariëns, Alvaro Mata

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Domenico LaurenzaBiodiscovery Institute, University of Nottingham, Nottingham, NG7 2RD, UK.
Fraser L MacraeDiscovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK.
Ieva SapjanskaiteBiodiscovery Institute, University of Nottingham, Nottingham, NG7 2RD, UK.
Alex HartleyBiodiscovery Institute, University of Nottingham, Nottingham, NG7 2RD, UK.
Bapan PramanikBiodiscovery Institute, University of Nottingham, Nottingham, NG7 2RD, UK.
Soraya Padilla-LopateguiSchool of Engineering and Material Science, Queen Mary University of London, London, E1 4NS, UK.
Felicity R A J RoseBiodiscovery Institute, University of Nottingham, Nottingham, NG7 2RD, UK.
Robert A S AriënsDiscovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK.
Alvaro MataBiodiscovery Institute, University of Nottingham, Nottingham, NG7 2RD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibrin, a crucial component in blood coagulation, supports wound healing by providing mechanical support, binding growth factors, and promoting the growth of different cell types. Here, we present an innovative approach to use peptide amphiphiles (PAs) as supramolecular organisers to guide fibrinogen polymerisation into fibrinogen-PA (FibPA) networks with hierarchically ordered morphologies and enhanced bioactive properties. PA-E3 (C

Indexed as

Bioactive materialsBiomaterialsCell therapiesCo-assemblyFibrinFibrinogenGrowth factorsMesenchymal stem cells (MSCs)Peptide amphiphiles (PAs)Supramolecular chemistrySupramolecular hydrogelsTGF-β1Tissue engineeringVEGF

Identifiers

PMID42668467
PMCPMC13524544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.