ArticleThe American journal of case reports2026
Subcentimeter Ileal Neuroendocrine Tumor Resection for Obscure Gastrointestinal Bleeding Followed by Pacemaker-Treated Sick Sinus Syndrome: A Case Report.
Article in The American journal of case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Obscure gastrointestinal bleeding (OGIB) denotes recurrent hemorrhage after nondiagnostic bidirectional endoscopy. In overt presentations with suspected small-bowel origin, capsule endoscopy, deep enteroscopy, and multiphase computed tomographic enterography (CTE) can improve lesion detection and operative planning. However, subcentimeter small-intestinal neuroendocrine tumors (siNETs) may remain undetected unless cross-sectional imaging enables targeted exploration. CASE REPORT A 72-year-old man presented with 2 days of melena and vague abdominal discomfort in the absence of hematemesis, hematochezia, weight loss, focal pain, or carcinoid features. Esophagogastroduodenoscopy and colonoscopy were nondiagnostic. Multiphase CTE localized an 11×8 mm enhancing mural nodule in the distal small bowel. Diagnostic laparoscopy with conversion to a limited laparotomy and intraoperative enteroscopy enabled precise localization, segmental ileal resection with mesentery, primary anastomosis, and appendectomy. Pathology findings comprised a grade 1 siNET measuring 0.8×0.6 cm with subserosal invasion, negative margins, and metastasis in 1 of 2 lymph nodes (pT3 pN1, Ki-67 index 2%). The postoperative surgical course was uncomplicated; however, profound bradycardia with syncope unmasked sinus node dysfunction, requiring dual-chamber pacemaker implantation, after which the patient remained clinically stable. CONCLUSIONS In older patients with overt OGIB and negative bidirectional endoscopy, early multiphase CTE can identify a small hypervascular ileal lesion, guiding targeted intraoperative enteroscopy and oncologic resection. Because nodal metastasis may occur despite a subcentimeter primary tumor, resection should include appropriate mesenteric lymphadenectomy. Vigilant perioperative cardiac rhythm monitoring is warranted because clinically significant bradyarrhythmias may require permanent pacemaker implantation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.