Evidence map›Paper›PMID 42667642›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2026

The Role of 1-3-Beta-D-Glucan in Predicting Pneumocystis jirovecii Pneumonia in Immunocompromised Children.

Markus Keldorfer, Raphael Ulreich, Johann Martensen, Patrick Faudon, Klaus Pfurtscheller, Siegfried Rödl, Robert Krause, Karl Dichtl, Volker Strenger, Stefan Hatzl

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Markus KeldorferPediatric Intensive Care Unit, Department of Children and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Raphael UlreichPediatric Intensive Care Unit, Department of Children and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Johann MartensenPediatric Intensive Care Unit, Department of Children and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Patrick FaudonPediatric Intensive Care Unit, Department of Children and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Klaus PfurtschellerPediatric Intensive Care Unit, Department of Children and Adolescent Medicine, Medical University of Graz, Graz, Austria.ORCID 0009-0008-3128-7514
Siegfried RödlPediatric Intensive Care Unit, Department of Children and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Robert KrauseDivision of Infectious Diseases, Department of Internal Medicine, Medical University of Graz, Graz, Austria.ORCID 0000-0001-6656-3648
Karl DichtlDiagnostic and Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria.
Volker StrengerDivision of General Pediatrics, Department of Children and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Stefan HatzlIntensive Care Unit, Department of Internal Medicine, Medical University of Graz, Graz, Austria.ORCID 0000-0001-6266-0512

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum 1,3-β-D-glucan (BDG) showed high negative predictive value (~99%) for Pneumocystis jirovecii pneumonia (PJP) in 106 non-human immunodeficiency virus immunocompromised children, but modest positive predictive value at low prevalence. These exploratory findings suggest BDG may help exclude PJP, pending prospective validation.

Indexed as

beta-GlucansImmunocompromised HostPneumocystis cariniiPneumonia, PneumocystisChildChild, PreschoolHumansPredictive Value of TestsProteoglycansbeta-Glucanspolysaccharide-KProteoglycans1,3-β-D-glucandiagnostic accuracyimmunocompromisednon-HIVpediatricPneumocystis jirovecii pneumonia

Identifiers

PMID42667642
PMCPMC13573584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.