Evidence map›Paper›PMID 42667592›Full record

ArticleIrish journal of medical science2026

Differentiating pulmonary sarcoidosis from pulmonary tuberculosis in clinical practice: Insights from routine blood tests.

İbrahim Koç, Deniz Çelik, Merve Bayram, Nur Akbulut, Özlem Yıldız, Altuğ Güner, Hasan Göğebakan

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Article in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

İbrahim KoçBursa City Hospital Pulmonary Medicine Clinic, Bursa, Turkey.ORCID http://orcid.org/0000-0003-4926-7331
Deniz ÇelikFaculty of Medicine Department of Pulmonology, Alanya Alaaddin Keykubat University, Alanya, Antalya, Turkey. deniz.celik@alanya.edu.tr.ORCID http://orcid.org/0000-0003-4634-205X
Merve BayramBursa City Hospital Pulmonary Medicine Clinic, Bursa, Turkey.ORCID http://orcid.org/0000-0001-9639-4929
Nur AkbulutBursa City Hospital Pulmonary Medicine Clinic, Bursa, Turkey.ORCID http://orcid.org/0009-0004-2735-4797
Özlem YıldızBursa City Hospital Pulmonary Medicine Clinic, Bursa, Turkey.ORCID http://orcid.org/0000-0002-1588-1256
Altuğ GünerBursa City Hospital Clinic of Rheumatology, Bursa, Turkey.ORCID http://orcid.org/0000-0001-7220-0288
Hasan GöğebakanBursa City Hospital Clinic of Rheumatology, Bursa, Turkey.ORCID http://orcid.org/0000-0002-3448-4838

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary sarcoidosis and pulmonary tuberculosis are both diseases that affect hundreds of thousands of people worldwide. Because both present with granulomatous inflammation in clinical practice, distinguishing tuberculosis from sarcoidosis can be difficult. This study hypothesised that parameters, such as monocyte, and albumin levels, and red blood cell distribution width and mean platelet volume ratio, can help differentiate sarcoidosis from tuberculosis. MATERIALS AND

methodsWe included 203 patients with sarcoidosis and 200 with tuberculosis in the study after excluding those with misdiagnoses or insufficient data. The neutrophil-lymphocyte ratio and platelet-lymphocyte ratio were obtained by dividing neutrophil and platelet levels by lymphocyte count. The blood parameters belong to the period of the first diagnosis before starting a treatment.

resultsThe sarcoidosis group had higher levels of mean platelet volume, platelet distribution width, and albumin, whereas they had lower levels of red blood cell distribution width, red blood cell distribution width/platelet distribution width, and red blood cell distribution width/mean platelet volume. Levels above 42.95 g/L for albumin and below 3.72 g/L for red blood cell distribution width/platelet distribution width promote sarcoidosis.

conclusionLower monocyte levels, red blood cell distribution width, red blood cell distribution width/platelet distribution width, and red blood cell distribution width/mean platelet volume, along with higher levels of mean platelet volume, platelet distribution width, platelets, albumin, and lymphocyte-monocyte ratio, may favour sarcoidosis over tuberculosis.

Indexed as

AlbuminMean platelet volumeMonocyteRed blood cell distribution width/platelet distribution widthSarcoidosisTuberculosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.