ArticleBrain imaging and behavior2026
Altered gray matter network segregation and disrupted interregional connectivity in children with persistent developmental stuttering: a graph-theoretical morphometric study.
Article in Brain imaging and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Developmental stuttering is a neurodevelopmental speech disorder characterized by speech disfluency and variable persistence into adolescence. While white matter and functional connectivity abnormalities have been widely reported, the topological organization of gray matter (GM) networks in affected children remains unclear. This study investigated GM morphological network alterations in children with persistent developmental stuttering (CWS) and examined their relationships with stuttering severity. Thirty-three CWS and thirty age- and sex-matched healthy controls underwent T1-weighted MRI. Individual GM morphological networks were constructed using Kullback-Leibler divergence of voxel-based morphometry data across 90 brain regions. Graph-theoretical analyses quantified global and local topological properties, and network-based statistics (NBS) were used to identify alterations in morphological connectivity. Both groups exhibited small-world topology; however, CWS showed significantly higher clustering coefficient(Cp), local efficiency (E
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