Evidence map›Paper›PMID 42667449›Full record

ArticleJournal of neuro-oncology2026

Extent of resection and craniopharyngioma recurrence: a volumetric analysis.

Sauradeep Sarkar, Sudharsan Vijayaraghavan, Sumit Thakar, Saritha Aryan

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Article in Journal of neuro-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Sauradeep SarkarDepartment of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Whitefield, Bengaluru, India. sauradeepsarkar@gmail.com.
Sudharsan VijayaraghavanDepartment of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Whitefield, Bengaluru, India.
Sumit ThakarDepartment of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Whitefield, Bengaluru, India.
Saritha AryanDepartment of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Whitefield, Bengaluru, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe optimal extent of resection (EOR) required to minimize recurrence risk in craniopharyngioma remains unclear. The objective of this study was to quantitatively evaluate postoperative tumor volume and EOR as determinants of progression-free survival (PFS) in surgically treated adamantinomatous craniopharyngiomas.

methodsWe retrospectively measured pre- and post-surgical tumor volumes in 60 patients using manual MRI-based segmentation. None received planned adjuvant radiotherapy. The median follow-up duration was 5 years. Clinical and volumetric variables were analyzed using Cox proportional hazards regression. Time-dependent receiver operating characteristic analysis at 3 years was also performed.

resultsTumor progression/recurrence occurred in 60% of patients. On univariable analysis, EOR was associated with improved PFS (HR 0.981 per 1% increase; 95% CI 0.966-0.997; p = 0.018), whereas increasing TV

conclusionsEOR, TV

Indexed as

CraniopharyngiomaNeoplasm Recurrence, LocalNeurosurgical ProceduresPituitary NeoplasmsAdolescentAdultChildFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedPrognosisRetrospective StudiesTumor BurdenCraniopharyngiomaExtent of resectionRecurrenceVolumetric analysis

Identifiers

PMID42667449

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.