Evidence map›Paper›PMID 42667398›Full record

ArticleCurrent microbiology2026

Protective Effect of Astaxanthin on Yeast Cells with Defects in Mitochondrial Function under Oxidative Stress and Aging.

A Jemima Princilly, S J Sudharshan, Bhavana Veerabhadrappa, Madhu Dyavaiah

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A Jemima PrincillyDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, 605014, India.
S J SudharshanDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, 605014, India.
Bhavana VeerabhadrappaDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, 605014, India.
Madhu DyavaiahDepartment of Biochemistry and Molecular Biology, Pondicherry University, Puducherry, 605014, India. madhud14@pondiuni.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria are involved in electron transport for energy production, generating cellular ATP through oxidative phosphorylation, which in turn generates reactive oxygen species (ROS). When mitochondrial ROS exceeds the ability of antioxidant enzymes to scavenge free radicals, it leads to mitochondrial dysfunction. In this study, we used astaxanthin, a well-known natural anti-aging compound, but its unique role in protecting yeast cells with mitochondrial dysfunction is poorly understood. Pre-treatment of astaxanthin significantly increased the viability of these mutant strains (bcs1∆, cox10∆, sdh2∆, sdh4∆, and sco1∆) when compared to H

Indexed as

MitochondriaOxidative StressSaccharomyces cerevisiaeAntioxidantsHydrogen PeroxideMembrane Potential, MitochondrialMicrobial ViabilityReactive Oxygen SpeciesSaccharomyces cerevisiae ProteinsXanthophyllsAntioxidantsastaxanthineHydrogen PeroxideReactive Oxygen SpeciesSaccharomyces cerevisiae ProteinsXanthophylls

Identifiers

PMID42667398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.