Evidence map›Paper›PMID 42667385›Full record

ArticleWorld journal of urology2026

Intrarenal pressure monitoring in retrograde intrarenal surgery for high-infectious risk populations.

Shuzo Hamamoto, Takaaki Inoue, Daisuke Kudo, Toshimitsu Matsuoka, Ryoji Takazawa, Yuji Kato, Takahiro Yanase, Rei Unno, Toshiki Etani, Kazumi Taguchi and 1 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

11 authors.

Shuzo HamamotoDepartment of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan. hamamo10@med.nagoya-cu.ac.jp.ORCID https://orcid.org/0000-0002-9968-7468
Takaaki InoueDepartment of Urology, Hara Genitourinary Hospital, Kobe, Japan.
Daisuke KudoDepartment of Urology, Hachinohe Heiwa Hospital, Hachinohe, Japan.
Toshimitsu MatsuokaDepartment of Urology, Hachinohe Heiwa Hospital, Hachinohe, Japan.
Ryoji TakazawaDepartment of Urology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan.
Yuji KatoDepartment of Urology, Saka Urology Hospital, Sapporo, Japan.
Takahiro YanaseDepartment of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.
Rei UnnoDepartment of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.
Toshiki EtaniDepartment of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.
Kazumi TaguchiDepartment of Urology, University of Alabama at Birmingham, Alabama, USA.
Takahiro YasuiDepartment of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya, 467-8601, Japan.

Funding

the Investigator-Sponsored Research Program of Boston Scientific ISRURO0116
6 · The paper itself

Abstract

purposeTo evaluate the feasibility of real-time intrarenal pressure (IRP) monitoring using the LithoVue™ Elite (LVE) ureteroscope and assess postoperative infectious complications after retrograde intrarenal surgery (RIRS) in patients with positive urine cultures.

methodsThis multicenter, single-arm, prospective cohort study (August 2023-October 2024) included patients with upper urinary tract calculi and positive preoperative urine cultures who underwent RIRS with real-time IRP monitoring via the LVE. Irrigation was adjusted to maintain IRPs below 30 mmHg. The primary endpoint was postoperative fever ≥ 38 °C. Secondary endpoints included systemic inflammatory response syndrome (SIRS), stone-free rates, ipsilateral flank pain scores, and complications.

resultsOf 148 eligible patients, 104 were enrolled. The median operative time and artificial intelligence-corrected IRP were 50 min (interquartile range: 36.8-80.0) and 13.3 mmHg (10.4-19.1), respectively. Postoperative fever occurred in 7.7% of patients, SIRS in 3.8%, and no septic shock was observed. Patients who developed postoperative fever were older (p = 0.019) and had longer preoperative ureteral stent indwelling times (p = 0.015). Univariable linear regression analysis demonstrated that higher body mass index (BMI), irrigation method, and ureteral access sheath tip location were significantly associated with higher intraoperative IRP (all p ≤ 0.005). Higher postoperative white blood cell counts and ipsilateral flank pain scores were also associated with elevated IRP (p = 0.010 and p = 0.032, respectively). In multivariable linear regression analysis, higher BMI and manual irrigation remained independent increased intraoperative IRP predictors (p = 0.042 and p = 0.009, respectively).

conclusionReal-time IRP monitoring using the LVE ureteroscope maintained low intrarenal pressures during RIRS and was associated with a low rate of postoperative fever in high-risk patients. These findings suggest that incorporating IRP monitoring into RIRS protocols is feasible and may improve pressure management in patients with positive urine cultures.

Indexed as

KidneyKidney CalculiMonitoring, IntraoperativePostoperative ComplicationsUrinary Tract InfectionsAdultFeasibility StudiesFemaleFeverHumansMaleMiddle AgedPressureProspective StudiesSystemic Inflammatory Response SyndromeIntrarenal pressureLithoVue™ ElitePositive urinary culturePostoperative infectious complicationsRetrograde intrarenal surgerySepsis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.