ArticleRespiratory medicine case reports2026
Humidifier lung diagnosed by integrating environmental assessment and inhalation provocation testing: a case with
Article in Respiratory medicine case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Humidifier lung is a rare phenotype of hypersensitivity pneumonitis caused by inhalation of aerosolized antigens from contaminated humidifiers, and identification of the causative antigen is often challenging. We report a case of humidifier lung in a 63-year-old woman who presented with recurrent episodes of fever, cough, and dyspnea. Chest computed tomography showed diffuse ground-glass opacities with mosaic attenuation, and bronchoalveolar lavage fluid revealed lymphocytosis. Her symptoms improved without treatment during hospitalization but recurred 5 hours after returning home, suggesting re-exposure to an environmental antigen. A humidifier challenge test reproduced symptoms, including fever, cough, and hypoxemia, necessitating systemic corticosteroid therapy. Fungal contamination was identified within the internal components of the humidifier, from which
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