ArticleCureus2026
Concurrent Kaposi Sarcoma and B-cell Lymphoma in an HIV-Negative Patient: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
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Abstract
We report the case of a 70-year-old non-immunocompromised male patient with coexisting classic Kaposi sarcoma (KS) and stage IV B-cell lymphocytic lymphoma. KS had been evolving insidiously since 2017 but was only confirmed in 2024 following a retrospective histological re-review. The patient received two lines of systemic chemotherapy, rituximab plus bendamustine (R-BENDA) followed by paclitaxel, with transient clinical responses before disease progression. This case suggests that the intrinsic immune dysfunction associated with chronic lymphocytic leukemia (CLL) may provide a permissive environment for human herpesvirus 8 (HHV-8) reactivation in the absence of classically recognized immunodeficiency states (HIV infection, iatrogenic immunosuppression, or primary immunodeficiency) and underscores the importance of histological re-review of atypical or long-standing cutaneous lesions.
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