Evidence map›Paper›PMID 42667030›Full record

ArticleBrain circulation

Early dobutamine response to delayed cerebral ischemia affected by vasospasm after subarachnoid hemorrhage: Serial cerebral blood flow analyses using O-15-water positron-emission tomography - A report of two cases.

Tatsushi Mutoh, Kaoru Sato, Junta Moroi, Tatsuya Ishikawa

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In one paragraph

Article in Brain circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Tatsushi MutohDepartment of Surgical Neurology, Research Institute for Brain and Blood Vessels, Akita Cerebrospinal and Cardiovascular Center, Akita, Japan.
Kaoru SatoDepartment of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels, Akita Cerebrospinal and Cardiovascular Center, Akita, Japan.
Junta MoroiDepartment of Surgical Neurology, Research Institute for Brain and Blood Vessels, Akita Cerebrospinal and Cardiovascular Center, Akita, Japan.
Tatsuya IshikawaDepartment of Surgical Neurology, Research Institute for Brain and Blood Vessels, Akita Cerebrospinal and Cardiovascular Center, Akita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delayed cerebral ischemia (DCI) which is mainly attributable to cerebral vasospasm, is a major cause of death and disability in patients with aneurysmal subarachnoid hemorrhage (SAH). Hemodynamic augmentation with vasopressors or inotropes is traditionally used in the clinical management of post-SAH DCI. Although the rationale for such treatment is to improve the regional cerebral blood flow (rCBF) to prevent secondary ischemia, brain-perfusion data underlying such systemic hemodynamic manipulation are limited. Here, we present two cases of SAH with symptomatic DCI caused by focal or multiple-vessel vasospasm to demonstrate the effects of dobutamine on serial rCBF measurements using

Indexed as

Cerebral blood flowdelayed cerebral ischemiadobutaminesubarachnoid hemorrhagevasospasm

Identifiers

PMID42667030
PMCPMC13524394

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.