Choroidal Vascular Characteristics in Subclinical Cushing Syndrome: A Cross-Sectional Pilot Study using Enhanced Depth Imaging Optical Coherence Tomography and Optical Coherence Tomography Angiography.

Eyupcan Sensoy, Berrak Sekeryapan Gediz, Sevde Nur Firat, Pinar Cicek Kaya

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Article in Journal of current ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Eyupcan SensoyDepartment of Ophthalmology, University of Health Sciences, Ankara Etlik City Hospital, Ankara, Türkiye.

Berrak Sekeryapan GedizDepartment of Ophthalmology, University of Health Sciences, Ankara Etlik City Hospital, Ankara, Türkiye.

Sevde Nur FiratDepartment of Endocrinology, Ankara Training and Research Hospital, Ankara, Türkiye.

Pinar Cicek KayaDepartment of Ophthalmology, University of Health Sciences, Ankara Etlik City Hospital, Ankara, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the potential choroidal vascular changes in newly diagnosed subclinical Cushing syndrome (SCS) patients and to assess whether choroidal parameters correlate with hormonal parameters. Methods: Twenty-one right eyes of 21 patients with SCS and 22 right eyes of 22 healthy individuals were included in the study. Results of the 1 mg dexamethasone suppression test, basal cortisol, basal adrenocorticotropic hormone, and 24-h urine-free cortisol levels were recorded from the patient files. Choroidal thicknesses (CTs) were measured from the subfoveal, 500 μm nasal, and 500 μm temporal quadrants with enhanced depth imaging-optical coherence tomography (OCT). The ImageJ program calculated the choroidal vascularity index (CVI). The choriocapillaris (CC) flow area was evaluated with OCT-angiography. The primary outcome measure was the CVI. Results: There were no significant differences in subfoveal, nasal, or temporal CT between groups ( Conclusion: According to the results of this study, subclinical hormonal changes in newly diagnosed SCS patients do not affect choroidal vascular status.

Indexed as

Choriocapillaris flowChoroidal thicknessChoroidal vascularity indexCortisolSubclinical Cushing syndrome

Identifiers

PMID42667020

DOI10.4103/joco.joco_271_25

PMCPMC13524391

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