ArticleInternational journal of cardiology. Heart & vasculature2026
FOCUS-ischemia: A real-world comparison of an ischemia-focused analytical strategy and conventional multiparametric stress CMR.
Article in International journal of cardiology. Heart & vasculature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Stress cardiovascular magnetic resonance (CMR) provides comprehensive assessment of myocardial ischemia and myocardial scar but remains limited by examination duration and accessibility. Whether an ischemia-focused analytical strategy preserves clinically relevant information compared with conventional multiparametric stress CMR remains uncertain. Objectives: To compare the real-world performance of Methods: A total of 717 consecutive patients undergoing clinically indicated stress CMR in the Nancy Ischemia Registry were included. Patients were stratified according to inducible ischemia and late gadolinium enhancement (LGE). Endpoints included early coronary revascularization within 30 days, late revascularization >30 days, and a composite outcome including death, Results: Inducible ischemia was strongly associated with downstream coronary management and adverse outcomes. Early revascularization rates were markedly higher in ischemic versus non-ischemic patients (18.1% and 17.0% vs 0.0% and 0.5%; Conclusions: An ischemia-focused analytical strategy derived from a conventional multiparametric stress CMR examination demonstrated similar discriminatory performance for coronary management-related outcomes. Because all patients underwent a conventional multiparametric stress CMR examination, the present study did not evaluate an abbreviated acquisition protocol. These findings should therefore be considered exploratory and hypothesis-generating.
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