ArticleRespiratory medicine case reports2026
A case of autoimmune pulmonary alveolar proteinosis in a patient with chronic nicotine vaping exposure.
Article in Respiratory medicine case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Pulmonary alveolar proteinosis (PAP) is a rare diffuse lung disorder characterized by accumulation of lipoproteinaceous surfactant material within alveoli, leading to impaired gas exchange. While autoimmune PAP, mediated by granulocyte/macrophage colony-stimulating factor (GM-CSF) autoantibodies, represents the most common form, emerging environmental exposures have been implicated as potential triggers. Electronic cigarettes (e-cigarette) use, or vaping, has recently been reported in a limited number of cases as a possible contributing factor in the development of PAP. We report a case of PAP in a young woman with a history of chronic vaping exposure, whose diagnostic evaluation confirmed the presence of circulating GM-CSF autoantibodies, supporting an autoimmune process linking the association between vaping and PAP.
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